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Researchers compare safety of sulfonylureas as diabetes treatment

A study in Diabetes Care showed that patients with type 2 diabetes on glyburide had lower rates of sudden cardiac arrest/ventricular arrhythmia, compared with those on glipizide. Researchers analyzed data from 1999 to 2010 US Medicaid claims involving 519,272 patients with diabetes using sulfonylureas and found that compared with glipizide, glimepiride had a propensity score-adjusted hazard ratio for sudden cardiac arrest/ventricular arrhythmia of 1.1.

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