German researchers interviewed young adults with early-onset type 1 diabetes and found that a 1 mmol/mol increase in A1C level was associated with 0.28 points higher score on the diabetes distress questionnaire, and each unit increase in score on the depression questionnaire at baseline was tied to a 0.49-mmol/mol increase in A1C levels. The findings in Diabetic Medicine also revealed that after adjusting for age, sex and socioeconomic status, women were more likely to have higher distress scores than men.