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Research links serum uromodulin levels to diabetic kidney disease

Patients with type 1 diabetes and higher serum uromodulin levels at baseline had lower odds of diabetic kidney disease and coronary artery calcification progression over 12.1 years, compared with those who had lower levels of serum uromodulin, according to a study in Diabetes Care. Researchers analyzed data from the Coronary Artery Calcification in Type 1 Diabetes study involving 527 patients, mean age of 39.6, and found those with CAC progression had longer diabetes duration, lower estimated glomerular filtration rates and higher systolic blood pressure than those without CAC progression.

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