People with frontotemporal dementia who had accumulation of abnormal proteins in the brain, especially TDP-43, had ninefold increased odds of committing criminal acts, compared with those who had tau accumulation, suggesting an association between TDP-43 and criminal behavior in FTD, researchers wrote in JAMA Network Open. The findings also showed a higher likelihood of repeat criminal offenses among those with FTD, compared with those with Alzheimer's disease.
Study links abnormal brain proteins to aggressive behavior in dementia
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