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Study identifies origins of Alzheimer's disease

Researchers at University of Texas Southwestern Medical Center found that tau molecules associated with Alzheimer's disease change shape before attaching to other tau proteins and enabling tau tangle formation, and aren't indistinctly shaped and harmful only when attached to other tau proteins, as previously believed. The findings in the journal eLife may allow early Alzheimer's detection and has prompted the development of therapies aimed at balancing tau before they change their shape, researchers said.

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