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Study evaluates mini-EXPLORER total-body PET scanner in primates

Researchers found that the mini-EXPLORER total-body PET scanner with long axial field of view yielded one-second frame visualizations of early F-18 FDG distribution in major blood vessels and organs of a juvenile rhesus monkey soon after injection, as well as acceptable image quality in a 40-minute scan at 18 hours after the injection, indicating the scanner's wide dynamic range and very low activity concentration imaging ability. The mini-EXPLORER, described in the Journal of Nuclear Medicine, has enabled researchers to develop data correction and reconstruction algorithms and applications that can be used in the human version of the scanner, said lead author Eric Berg.

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