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PET may help guide breast cancer treatment

Researchers found that PET with the radiotracer F-18 FluorThanatrace was able to provide effective PARP-1 level measurement and visualization in all breast cancer tumors and metastases in women with various breast cancer subtypes, while another study showed that fluciclovine PET was able to monitor tumor glutamine level changes brought by the glutaminase inhibitor CB-839 in women with triple-negative breast cancer. "These studies are important steps toward developing much-needed, non-invasive imaging tests to help measure and predict inhibitor responses and guide treatments for women with a wide range of breast cancers," said Dr. David Mankoff, co-senior author of both studies presented at the San Antonio Breast Cancer Symposium.

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