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F-18 FDG micro-PET imaging in octopuses may aid regenerative medicine

Italian researchers who used F-18 FDG micro-PET found that octopuses had up to a threefold increased radiotracer uptake in regenerating arms at the level of areas with high proliferation, indicating that actively dividing cells are present in the peripheral nervous tissue, blastema and muscles of regenerating tissues. The study in the Journal of Nuclear Medicine "represents a first step toward the use of nuclear medicine imaging techniques in new emerging research areas such as neurobiology of invertebrates and animals with particular relevance in the field of regenerative medicine," researchers wrote.

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