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Many childhood cancer survivors develop chemo-induced neuropathy

An Australian study in JAMA Neurology showed that 50.5% of childhood cancer survivors who underwent neurotoxic chemotherapy had clinical abnormalities in Total Neuropathy Scores. Researchers also found smaller lower limb sural sensory amplitudes, suggesting a reduced number of functioning axons, among those exposed to neurotoxic chemotherapy, compared with controls, while abnormalities were more prevalent among those exposed to cisplatin.

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