Human brain tissue with Alzheimer's disease and mouse models with Alzheimer's-associated amyloid-beta protein had constricted capillaries, reducing blood flow similar to levels observed in other brain regions affected by Alzheimer's, according to a UK study in the journal Science. The findings prompted researchers to suggest that capillary constriction, which hampers delivery of oxygen and glucose to the brain, could be associated with Alzheimer's-related cognitive decline.
Capillary constriction linked to cognitive decline in Alzheimer's
Sign up for SNMMI SmartBrief
Nuclear medicine and molecular imaging news
Get the intelligence you need: news and information that is changing your industry today, hand-curated by our professional editors from thousands of sources and delivered straight to your inbox.