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Link between cognitive reserve, later amyloid-beta accumulation studied

Older adults with at least a college education and any amyloid-beta protein deposition levels scored at least one standard unit higher in cognitive tests, compared with those who didn't graduate high school, regardless of amyloid-beta accumulation, but there was no association between midlife cognition scores and late-life amyloid-beta accumulation, according to a study in the Journal of Alzheimer's Disease. "Our data suggest that more education seems to play a role as a form of cognitive reserve that helps people do better at baseline, but it doesn't affect one's actual level of decline," said researcher Dr. Rebecca Gottesman.

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