Cognitively healthy or very mildly impaired older adults with reduced levels of slow-wave sleep had higher tau accumulation on their brain PET scans and an increased tau-to-amyloid ratio in their cerebrospinal fluid, which are associated with Alzheimer's disease, researchers reported in Science Translational Medicine. The findings suggest that sleep monitoring could accompany brain scans and CSF analysis in determining early Alzheimer's symptoms, said study lead author Dr. Brendan Lucey.
Reduced slow-wave sleep may be linked to early Alzheimer's development
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