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Early HPV clearance boosts cervical cancer outcomes

A study in the journal Cancer showed that women with cervical cancer and early post-therapy human papillomavirus clearance had 76.9% two-year pelvic control and 80.9% two-year overall survival, compared with 50.2% two-year pelvic control and 52.2% two-year OS among those with persistent HPV expression. Researchers also found that among those with complete response on post-therapy PET and early HPV clearance, the two-year OS rate was 95.6%, compared with 66.7% among those with persistent expression, while the lowest two-year OS rate was found among those with persistent expression and no PET complete response.

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