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Melatonin levels tied to nonmotor symptoms in Parkinson's

People with Parkinson's disease had higher blood melatonin levels than healthy controls, and reduced melatonin levels among those with Parkinson's correlated with cardiovascular and gastrointestinal problems, sleep disturbances and elevated levodopa dosages but not disease severity, according to a study in Frontiers in Neuroscience. The findings indicate that blood melatonin levels might be associated with nonmotor Parkinson's symptoms, but more studies are needed, researchers wrote.

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