A systematic review and meta-analysis, published online in Alimentary Pharmacology & Therapeutics, including 53 studies involving 7,917 pregnancies in women with inflammatory bowel disease and 3,253 healthy control pregnancies found an increased risk of adverse pregnancy outcomes in women with IBD, including gestational diabetes and preterm rupture of membranes. The analysis also found an almost twofold increase in the number of cesarean deliveries among pregnant IBD patients compared with controls, but no higher risk of placenta-related adverse outcomes.
Review ties IBD in pregnancy to higher risk of adverse outcomes
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