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Methylphenidate may affect brain development in boys with ADHD

Boys with attention-deficit/hyperactivity disorder ages 10 to 12 who received methylphenidate had elevated white matter fractional anisotropy after 16 weeks compared with those who were given placebo, but methylphenidate wasn't tied to such brain changes among young adult men with ADHD ages 23 to 40, according to a Dutch study in Radiology. The findings should prompt the use of methylphenidate prescriptions only for children significantly affected by ADHD, said researcher Liesbeth Reneman.

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