SARS-CoV-2 infections in domesticated animals can be managed, but wild animals could be exposed to SARS-CoV-2 through contact with infected people or contaminated waste water, says epidemiologist Jonathan Epstein, vice president for science and outreach at EcoHealth Alliance. Infections in wild animals could spill back to humans as new variants, and zoos can conduct retrospective serologic surveys to learn how the virus behaves in different species, says Tracey McNamara, a professor of pathology at the Western University of Health Sciences College of Veterinary Medicine.