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Rare drug-resistant E. coli found in Philadelphia-area dogs, cats

Bacterial samples from some dogs and cats treated at PennVet's Ryan Veterinary Hospital in the summer of 2018 contained carbapenem-resistant Escherichia coli, but the mechanism of resistance was unexpected. Researchers at the FDA and the University of Pennsylvania's School of Veterinary Medicine expected to see the same genetic mutation in the animals as had been found in area residents with carbapenem-resistant and carbapenemase-producing Enterobacteriaceae infections, but instead they found a different mutation: New Delhi metallo-beta-lactamase-5, which had never before been found in companion animals in the US.

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