Rats and mice infected with Toxoplasma gondii lose their fear of cats, and some studies have shown that people infected with the parasite may also be drawn to risky behavior, but recent research suggests the behavior may be due to the host's immune reaction instead of the parasite itself. The hypertension drug guanabenz reduced both brain cyst count and risky behavior in mice with latent toxoplasmosis, but in mice engineered to be susceptible to Toxoplasma, cyst count was not reduced but risk-taking was, suggesting that inflammation drives the behavior.
Immune reaction to Toxoplasma might be what drives risky behavior
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