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Clinical trial to test breast cancer drug against canine lung cancer

A study published in Clinical Cancer Research found that the breast cancer drug neratinib is effective against canine pulmonary adenocarcinoma. The researchers found a novel mutation of the HER2 gene in about half of the dogs with CPAC they tested and found the drug inhibits the gene's activity, and researchers at Ohio State University's College of Veterinary Medicine are leading a clinical trial.

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