A synthetic DNA vaccine that targets glycoproteins on the surface of the Ebola virus immediately stimulated a strong immune response in monkeys that continued for a year after the last dose, researchers reported in the Journal of Infectious Diseases. The vaccine was delivered directly into the skin.
Scientist in China said they used CRISPR gene editing to breed mice with same-sex parents, shedding light on a biological mechanism that prevents reproduction in the absence of both maternal and paternal DNA. The pups with two mothers grew to adulthood and were able to bear pups of their own, but none of the bipaternal pups survived to adulthood, the researchers reported in Cell Stem Cell.
Anesthesia causes changes in circadian rhythms and hormone levels in laboratory animals that could confound experimental results, and anesthesia timing should be standardized across individual studies, says Guy Warman, whose study on the effects of anesthesia was published in Experimental Neurology.
As airlines work to accommodate the demands of travelers who bring an increasingly diverse set of comfort animals on board, they are also yielding to pressure from animal rights groups and refusing to transport animals that contribute to research that seeks to cure cancer and other devastating diseases. Existing laws mean "that if the airline is willing to ship one woman's pig to help her feel comfortable and relaxed, it must also ship other similar animals being transported for different purposes -- including medical research," writes George Landrith. The Department of Transportation should enforce the law, he argues, and ensure animals get where they are needed for lifesaving research.
Environmental scientist David Keith, atmospheric physicist Joanna Haigh and environmental physiologist Christine Lattin have been repeatedly harassed and threatened on social media and via email. All try to ignore personal attacks and address false claims with respect and honesty, and Lattin says she has tried to make her research more accessible to a lay audience to improve public understanding.
A clinical trial is testing the safety of focused ultrasound to breach the blood-brain barrier during surgery to treat glioblastoma, and another is testing focused ultrasound in newly diagnosed glioblastoma patients undergoing chemotherapy. The approach, which has been successful in nonhuman primates, allows cancer-killing drugs to cross the blood-brain barrier and could improve survival of brain cancer patients.
A new publication released by the National Academy of Medicine highlighted the importance of a system's EHR interoperability and health data exchange capabilities when purchasing health IT devices and solutions. The group's health care industry experts recommend purchasing health IT tools from different vendors, implementing procurement strategies or certain standards when selecting or purchasing EHRs and health IT tools, creating interoperability steering groups across the organization and developing procurement specifications.
HHS' Office for Civil Rights imposed a $16 million fine against health insurer Anthem stemming from a data breach incident in January 2015 that compromised the electronic protected health information of almost 79 million people. According to the OCR's investigation, Anthem failed to implement adequate minimum access controls, did not conduct a risk analysis across the organization and failed to identify and react to known or suspected security issues.
HIMSS and AcademyHealth will team up on Health Datapalooza 2019, the 10th annual health data and technology convention held by AcademyHealth. "HIMSS is proud to join AcademyHealth in the Health Datapalooza and in working together to ensure the secure and meaningful transformation of data into new capabilities that deliver innovation in health transformation," said HIMSS President and CEO Hal Wolf.
Researchers tested an mHealth platform called HealthMpowerment.org, a health education tool optimized for use on mobile devices and intended to decrease high-risk behavior among black men who have sex with men. The study involved 474 BMSM, some HIV-negative and some HIV-positive, who were randomly assigned to two groups, and data showed that after a three-month period, there was a 32% lower rate of anal intercourse without condom use among those using the platform compared with those not using the tool.
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