A study in Diabetes Care showed a 24% increased risk for type 2 diabetes for every one standard deviation increase in fasting plasma glucose coefficient of variation. Researchers evaluated data from the Korean National Health Insurance System involving 131,744 people without diabetes at baseline and found that older males who completed little physical activity, had a higher incidence of dyslipidemia and hypertension, drank alcohol and smoked had greater variation of fasting plasma glucose levels.
Adults with type 1 diabetes who used inhaled insulin had less time spent in hypoglycemia and a lower glucose standard deviation at four weeks, compared with those on insulin aspart, according to a study in Diabetes Technology & Therapeutics. Researchers recruited 60 diabetes patients and found those in the inhaled insulin group also lost more weight.
A study presented at the American Society for Bone and Mineral Research's annual meeting found that men with type 2 diabetes had higher advanced glycation end-product content in the cortical bone of the femoral neck, which is associated with reduced bone strength, compared with those without diabetes. Researchers analyzed 65 men with and without diabetes and found no association between AGE content and A1C levels, but increased AGE content correlated with lower initiation toughness.
A device that uses Raman spectroscopy to measure blood glucose levels through the skin by producing a "molecular fingerprint" has been developed by researchers from MIT and the University of Missouri School of Medicine. They conducted a study with individuals without diabetes and found that the device and a finger prick test had similar efficacy in assessing blood glucose levels.
Dutch researchers examined dynamic F-18 flutemetamol PET scans from older adults with normal cognition and found that images quantified using nondisplaceable binding potential yielded "good" interreader agreement, compared with "moderate" agreement using standard uptake value ratio imaging. The findings in the Journal of Nuclear Medicine also showed reader discordance in only 15 cases with BPND images, compared with 35 SUVR cases, 91% of which were negative based on semiquantitative measurements.
Women who took aspirin daily were 10% less likely to develop ovarian cancer, compared with those who didn't, researchers reported in the Journal of the National Cancer Institute. Another study in The Lancet Oncology showed up to 30% improved survival among women with ovarian cancer who received aspirin or nonaspirin nonsteroidal anti-inflammatory drugs, such as naproxen and ibuprofen, after diagnosis.
A breakthrough computer model combining brain biomechanics and biochemistry that was developed by researchers at Stevens Institute of Technology in New Jersey was able to map and simulate how toxic proteins associated with Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis spread in the brain. The findings were published in the journal Physical Review Letters.
Young healthy mice on a ketogenic diet had significantly better neurovascular integrity involved in cognitive ability, as well as significantly improved removal of amyloid-beta plaques associated with Alzheimer's disease, compared with those that were given a regular diet, according to a study in Frontiers in Aging Neuroscience. Researchers also found better gut microbiome balance and reduced body weight and blood glucose levels among those in the ketogenic diet group.
Mediso Medical Imaging Systems and the National Physical Laboratory in the UK have entered a research collaboration that will enable NPL to use Mediso's AnyScan SPECT/CT/PET system in developing unique measurement abilities and provide the world's first triple-modality scanner directly calibrated using primary radioactivity standards. Mediso will apply the study's findings to its imaging products, said managing director Istvan Bagamery.
Support funding for medical and social services for persons living with HIV/AIDS from the US federal government have exceeded more than $2 billion in fiscal year 2018. More than $820 million went to states for the AIDS Drug Assistance Program, which provide medications to patients who are low-income and are underinsured or uninsured.
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