The Trump administration reportedly is working on a list of proposals to deter southern border crossings, one of which would give families a choice between staying imprisoned together or relinquishing child custody. The strategies are said to be efforts to overcome legal and political problems with the current separation policy.
Researchers found an association between high baseline metabolic syndrome severity Z score and individual component scores and an increased risk for incident type 2 diabetes and cardiovascular disease. The findings in Diabetes Care, based on 2,476 prediabetes patients from the Diabetes Prevention Program, revealed those in the lifestyle modification group had the greatest reduction in severity effect sizes during the first three years of follow-up, followed by the metformin and placebo groups.
A study in The BMJ showed that 9.7% of US adults were diagnosed with any form of diabetes in 2016 and 2017, 0.5% of whom had type 1 diabetes and 8.5% had type 2 diabetes. Researchers analyzed data from the 2016 and 2017 versions of the National Health Interview Survey involving 58,186 adults ages at least 20 and found those with type 1 diabetes had lower body mass index and higher levels of education, and were generally younger than those diagnosed with type 2 diabetes.
Individuals who developed diabetes had significantly higher mean fasting plasma glucose levels and body mass index and lower single point insulin sensitivity estimator 10 years before diagnosis, compared with those who didn't develop diabetes, according to a study in the Journal of the Endocrine Society. Japanese researchers evaluated 27,392 health examinees without diabetes and found that 10 years before diagnosis, those who developed prediabetes also had higher mean FPG and BMI and lower SPISE than those who didn't develop prediabetes.
A study in JAMA Network Open showed that elite performers, or individuals ages older than 70 who had aerobic fitness in the top 2.5%, had an almost 30% reduced mortality risk, compared with high performers. Researchers recruited more than 122,000 patients and found that not exercising at all appears to be worse for health than diabetes, high blood pressure, heart disease, cholesterol and smoking.
A study in the Journal of the American College of Radiology showed that nuclear medicine call centers failed to explain FDG-PET/CT exam guidelines and preferred examination times to patients with diabetes 47% and 91% of the time, respectively, and only 29% of phone calls contained discussions about glucose thresholds. The findings should prompt more studies to provide the best recommendations, as well as increased advocacy from national organizations to ensure proper communication with patients with diabetes, researchers said.
The medical imaging-based Subtype and Stage Inference machine learning algorithm developed by University College London researchers was able to distinguish several frontotemporal dementia subtypes and three different Alzheimer's disease subtypes that matched those found in brain tissue post-mortems. The approach, described in Nature Communications, may improve dementia diagnosis and prediction of disease progression, as well as prompt better dementia treatments, researchers said.
Canadian researchers found that whole-body fluorocholine-PET/MRI with the gadolinium-enhanced T1-weighted volumetric interpolated breath-hold exam yielded the highest detection rate for conspicuous lesions and the highest time efficiency in staging patients with high-risk prostate cancer, compared with PET/MRI with whole-body diffusion-weighted imaging, coronal T2-weighted turbo inversion-recovery magnitude or coronal T1-weighted 3D Dixon. The findings in the American Journal of Roentgenology may also be applied to prostate-specific membrane antigens and other PET radiotracers, researchers wrote.
UK researchers found that about 80% of men with locally advanced prostate cancer who received hormone therapy and radiation therapy achieved three-year survival, compared with 70% of those only given hormone therapy. The findings in The Lancet "could and should change standard of care worldwide," said lead researcher Dr. Chris Parker.
SHINE Medical Technologies received a delivery of a Phoenix custom-designed production accelerator at its radioisotope production campus in Janesville, Wis., which is expected to help in the manufacturing of molybdenum-99 in the US. The production facility will use eight Phoenix neutron generators, and construction is set to begin next year, while commercial Mo-99 production should start in 2021, according to SHINE.
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