Amgen and Allergan announced that the first anticancer biosimilars will now be available in the US, consisting of Mvasi, or bevacizumab-awwb, a biosimilar to Avastin, or bevacizumab, which is approved by the FDA for five cancer-related indications, and Kanjinti, or trastuzumab-anns, a biosimilar to Herceptin, or trastuzumab, indicated for HER2-overexpressing oncologic diseases such as breast cancer and for metastatic gastroesophageal junction or gastric adenocarcinoma. Both biosimilars will cost 12% to 15% less than their branded counterparts.
West Nile virus was confirmed as the cause of loon deaths at lakes in Northeastern Minnesota, and scientists are exploring whether it is contributing to a ruffed grouse population decline. Veterinarian Arno Wuenschmann, a pathology professor at the University of Minnesota's College of Veterinary Medicine, says people with horses should vaccinate their animals for the virus and should take precautions to prevent exposure to mosquitoes.
The Canadian Food Inspection Agency quarantined two sheep flocks in Alberta for classical scrapie, and sheep in the flock are being tested for genetic resistance to the transmissible spongiform encephalopathy. Sheep producers should work with a veterinarian to prevent scrapie, says Alberta Lamb Producers Chair Darlene Stein.
Primary care physicians should offer education or counseling to prevent smoking among teens and children, because 90% of smokers have their first cigarette before they are 18, according to a draft recommendation from the US Preventive Services Task Force. Many young people don't see e-cigarettes as harmful, so prevention is especially important when discussing them, said Thomas Houston, M.D., former chair of the AAFP Commission on Health of the Public and Science and the Academy's now-disbanded Smoking Cessation Advisory Committee.
A federal judge upheld a Trump administration rule extending the duration of short-term health plans, which do not comply with the Affordable Care Act's coverage requirements, from three months to one year, noting the rule's potential negative impact is minimal "but its benefits are undeniable." The plaintiffs say they will appeal the ruling.
The CMS said it has updated the Medicaid and Children's Health Insurance Program Scorecard data to reflect information on postpartum care, well-child appointments, adult hospitalizations involving diabetes and more. "More states are voluntarily reporting their health outcomes in the scorecard, and the new data is leading us into an era of increased transparency and accountability," CMS Administrator Seema Verma said.
Researchers performed three random blood glucose tests within 12 months on more than 900,000 Veterans Administration patients and found that those who had a minimum of two glucose measurements of at least 115 mg/dL within a year were more likely to be diagnosed with diabetes in the next five years, while patients whose readings reached 130 mg/dL had an even higher risk of developing the condition. Findings published in PLOS ONE showed random blood glucose tests "could appropriately prompt high-yield, focused diagnostic testing and improve recognition and treatment of prediabetes and early diabetes," stated lead author Mary Rhee.
Teens and young adults with type 1 diabetes and low disturbed eating behaviors had the highest self-management scores and the lowest scores on diabetes distress, A1C levels and depressive symptoms, compared with least adaptive scores among those with persistent DEB, and intermediate outcomes among those with increasing and decreasing DEB, according to a study in Diabetes Care. Researchers also found that diabetes self-management over time was stable among those in the low and persistent DEB groups, improved among those in the decreasing DEB group and worsened among those in the increasing DEB group.
Researchers surveyed 18,769 adults enrolled in WW International, a commercial weight management program, and found that 63.5% of the participants experienced weight stigma and 46.3% reported experiencing weight stigma in childhood or adolescence. Findings published in Obesity Science and Practice also showed that younger participants, women and those with a higher body mass index had increased weight bias internalization, with those who had a romantic partner or were widowed and black participants had lower weight bias internalization.
Premature adrenarche was not tied to an increased risk of metabolic syndrome, dyslipidemia, hypertension, hepatosteatosis, atherosclerosis or low-grade inflammation but women with PA did have a higher prevalence of insulin resistance and acanthosis nigricans, higher A1C levels and more central fat mass than controls, according to an analysis in the Journal of the Endocrine Society. Researchers said that the risk of decreased insulin sensitivity in women with PA is likely tied to the increased central adiposity in adulthood, rather than prepubertal factors.
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