Researchers found that a convolutional neural network with 4D flow cardiac MRI shortened interpretation times from 15 minutes to 34 seconds in children with cardiac abnormalities. The approach, described at the International Society for Magnetic Resonance in Medicine virtual annual meeting, may boost workflows and treatment planning for pediatric cardiac atypicalities, researchers said.
It is important for children to get daily exercise if school is online and they are learning at home, but it does not always have to be outside, said registered dietitian Juan Trevino. Jumping rope and just walking around the house are options, Trevino said, adding that exercise is good for both physical and emotional health.
Individuals with systolic orthostatic hypotension may have an increased risk of developing dementia, according to a study in Neurology. "Systolic OHYPO and visit-to-visit variability over time of postural changes in [seated systolic BP] were associated with an increased risk of dementia of almost 40%," the researchers said.
This study set out to examine the magnitude of the effect of statin therapy on venous thromboembolism recurrence across a large statewide population. Patients with venous thromboembolism and a documented prescription for a statin medication were found to have a significantly decreased risk of venous thromboembolism recurrence. Thus, statins may be considered as adjuvant therapy in secondary prevention of venous thromboembolism recurrence.
COVID-19 has added an enormous toll to the existing challenge of diabetes care worldwide, as individuals with diabetes and other chronic conditions are at increased risk of hospitalization and death. In particular, racial/ethnic minorities have been disproportionately impacted by diabetes and COVID-19. Comprehensive management of diabetes and common comorbidities is crucial to reducing morbidity and mortality rates. Socioeconomic factors should be acknowledged and addressed at multiple levels to reduce diabetes & COVID-19 disease burdens. Lessons learned during this pandemic should influence the future of both disaster-based and routine diabetes care.
Obesity is associated with myocardial fibrosis and impaired diastolic relaxation. Normal coronary vascular endothelial function is integral in mediating diastolic relaxation, and recent work suggests increased activation of the ECMR is associated with impaired diastolic relaxation. As the endothelial Na+ channel (EnNaC) is a downstream target of the ECMR, we investigate whether EC-specific deletion of the critical alpha subunit, αEnNaC, would prevent diet induced-impairment of diastolic relaxation in female mice. These findings show that WD feeding in female mice promotes activation of EnNaC in the vasculature leading to increased cardiomyocyte stiffness and diastolic dysfunction.
Texas legislative restrictions on medication abortion disproportionately prevented low-income patients and those living far from open clinics from using this method.
Data from the LGBTQ National Teen Survey was analyzed to identify variations in bias-based bullying (based on body weight, gender, religion, disability, gender typicality, sexual orientation) experienced by sexual and gender minority adolescents attending schools with and without a gay-straight alliance. Approximately 73% of sexual and gender minority adolescents were bullied for stigmatized identities other than gender or sexual orientation, with students at schools with gay-straight alliances less likely to report multiple forms of bias-based bullying.
To confirm the diagnosis of hypertension in children and adolescents, recent guidelines recommend 24-hour ambulatory blood pressure monitoring (ABPM); however, wearing a BP monitor for a prolonged period is not always well tolerated. Automated office BP (AOBP), a series of BP measurements by an automated device, may provide an alternative. In a records review of patients in a pediatric hypertension clinic, Hanevold et al found that AOBP may aid in the diagnosis of daytime ambulatory hypertension, but was less useful for diagnosis of white coat hypertension. However, it may be useful when access to ABPM is limited.
To validate a composite asthma control tool that includes impairment and risk assessments, 442 patients aged ≥12 years with physician-diagnosed asthma completed 15 impairment and risk questions with dichotomized yes/no responses. The final AIRQ™ comprises 10 equally-weighted yes/no impairment and risk questions. The final 10-item models yielded receiver operating characteristic curves of 0.94 to identify well-controlled versus not well-/very poorly controlled and 0.93 to identify well-/not well-controlled versus very poorly controlled asthma, as reflected by the ACT™ plus prior-year exacerbations standard. Cut points of 0-1, 2-4, and 5-10 best represented well-, not well-, and very poorly controlled asthma. AIRQ™ is a rigorously validated composite measure of asthma control designed to identify adults and adolescents with varying degrees of asthma control.