The CDC said 346 Americans who were placed under mandatory quarantine at two military bases in California after being evacuated from Wuhan, China, have been medically cleared and can now return to their homes. Around 500 passengers of the Diamond Princess cruise ship docked in Yokohama, Japan, who didn't show any symptoms and tested negative for the virus that causes COVID-19, were also allowed to leave the ship after being quarantined since Feb. 3. The virus has killed at least 2,000 people and infected over 75,000.
An HHS study found the rate of sepsis hospitalization among Medicare beneficiaries climbed by 40% between 2012 and 2018, and in 2018 alone, these hospitalizations cost the program more than $41.5 billion. Researchers said the trend was not fully explained by growing enrollment, and HHS estimated the cost for inpatient and skilled nursing care related to sepsis would surpass $69 billion for 2019.
The stress of helping people is being felt by clergy across faiths as they're also confronted with anti-Semitic and anti-Muslim messages, scandals affecting morale and other challenges. "Had I known the ugly side of ministry -- the hospital visits, burying the dead, being in the room when someone is dying and trying to comfort their family ... I don't think I would have accepted being a pastor," says Rodney McNeal, who's also a hospital social worker.
The FDA and India's government have teamed up in Operation Broadsword to block around 500 shipments containing illegal opioids and counterfeit drugs and medical devices from entering the US. The agency and India examined around 800 shipments entering the US in January and found that many had been shipped through third-party countries to prevent detection.
Veterinarian Elizabeth Rozanski is leading a clinical trial at Tufts University's School of Veterinary Medicine of a treatment for idiopathic pulmonary fibrosis, a lung disease that affects West Highland terriers and other breeds, as well as people. The treatment, sobetirome, was developed to reduce cholesterol and works like a thyroid hormone in animal models of pulmonary fibrosis, and Dr. Rozanski is partnering with Yale University School of Medicine physician Naftali Kaminski on the study.
Viruses have jumped between people and animals since humans first began eating, farming with and living among animals, and as long as people coexist with animals, zoonosis will continue, says veterinarian Tony Goldberg, a professor at the University of Wisconsin-Madison School of Veterinary Medicine. A single point mutation may be all it takes for an animal virus to gain the ability to infect human cells, and predicting point mutations is difficult, says microbiologist Sara Cherry.
A study in the Journal of the American Heart Association found that sodium-glucose cotransporter 2 inhibitors could help protect against major adverse cardiac events like heart failure and cardiovascular death, as well as death from any cause, among individuals with type 2 diabetes. Researchers evaluated data from 38,723 patients with type 2 diabetes and wrote that "SGLT2 inhibition should be considered in all patients with type 2 diabetes mellitus and elevated risk of cardiovascular disease, even in the absence of established disease."
Australian researchers analyzed the incidence and prevalence of thyroid disease in a group of 1,617 adults with diabetes and discovered that around 3% acquired thyroid disease during a seven-year follow-up, emphasizing the need for regular thyroid function testing. The findings, published in Clinical Endocrinology, also showed that "mild abnormalities of thyroid function test results were frequently transient, so that appropriate repeat testing and careful interpretation of the results is needed if overdiagnosis is to be avoided."
A study in Frontiers in Endocrinology found that a continuous behavioral-lifestyle intervention in pregnancy assisted by a smartphone app improved dietary intakes, physical activity, and motivation to engage in exercise. The findings, based on data from 565 pregnant women with overweight and obesity, showed that dietary glycemic index and glycemic load at 28 weeks' gestation -- as well as mean daily energy, carbohydrates, sugars, free sugars, fat, saturated fat, calcium and sodium intake -- were significantly lower among those in the intervention group.
A "nudge" in EHRs reduced the number of inappropriate tests for hospital-onset Clostridioides difficile infection at four hospitals, researchers reported in Infection Control & Hospital Epidemiology. An alert notified health care providers ordering a CDI test if the patient received a laxative or stool softener in the previous 24 hours, and the percentage of tests deemed inappropriate declined by a percentage point and monthly CDI orders fell 21% after the nudge was implemented.
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