The prevalence of bloodstream infection-related hospitalizations among US youths younger than 19 didn't significantly drop between 2009 and 2016, while the rate of infections due to methicillin-sensitive Staphylococcus aureus and Escherichia coli significantly rose during the same period. The rate of infections due to Enterococcus species and Streptococcus pneumoniae declined, according to a study in Clinical Infectious Diseases.
Researchers found that the new Pediatric Asthma Risk Score had 11% increased sensitivity in predicting asthma in children with mild to moderate risk, compared with the Asthma Predictive Index, even though both tools similarly predict asthma in high-risk youths. The findings in the Journal of Allergy and Clinical Immunology were based on data involving 762 youths born from 2001 to 2003 whose parents had one or more allergy symptoms.
A study in The New England Journal of Medicine showed that men with localized prostate cancer who underwent radical prostatectomy had a mean of 2.9 additional years of life at 23 years' follow-up, compared with those in the watchful waiting group. However, researchers found a five times and 20 times increased mortality risk among those who had radical prostatectomy with extracapsular extension and a Gleason score higher than 7, respectively.
Adults with and without established cardiovascular disease who received ezetimibe with statin therapy had a modestly lower risk of major adverse CV events and all-cause mortality, compared with those who took statins alone, researchers reported in the Cochrane Database of Systematic Reviews. The findings were based on a systematic review and meta-analysis of 26 studies with 23,499 total individuals.
Guardant Health and AstraZeneca entered into a multiyear agreement that will allow them to jointly develop blood-based companion diagnostic assays to determine non-small cell lung cancer patients' response to Tagrisso, or osimertinib.
Dosing has been initiated for Aptevo Therapeutics' Phase I/Ib study to assess its anti-CD123xCD3 bispecific antibody candidate APVO0436 as a treatment for patients with high-grade myelodysplastic syndrome and acute myeloid leukemia. The study's estimated primary completion date is August, according to the ClinicalTrials.gov website.
Pennsylvania social worker Melody Ray wrote a book to help children understand the loss of family members to substance abuse when she became frustrated by the lack of appropriate material. "Someone I Love Died From A Drug Overdose" depicts a mother's explanation to her son about his father's death from an overdose, gently but without resorting to vague euphemisms.
Laws against sleeping in public by homeless people are an unjust and ineffective approach to a problem that would be better solved by providing housing, an advocate told a Colorado group. Tristia Bauman, staff attorney for the National Law Center on Homelessness and Poverty, spoke at the release of a white paper criticizing a Durango, Colo., ban on camping.
Courtney Allen has become a leader in Maine's recovery movement, three years after admitting herself to detox, participating in family court and temporarily relinquishing custody of her two children. The 25-year-old is now a mentor at Augusta Family Treatment Drug Court and also counsels classmates at the University of Maine, where she is majoring in justice advocacy and mental health.
More than half of Massachusetts adults seeking mental health or addiction care in recent months had trouble getting it, even though most of them were insured, according to a survey. Providers in many cases refused either to accept the insurance or to take new patients, the Blue Cross Blue Shield of Massachusetts Foundation reported.