The Multiple Myeloma Research Foundation has launched its online Direct-to-Patient Registry, which will allow patients with multiple myeloma to submit their health data securely to the foundation's data repository, the MMRF CureCloud. The repository will include information from other foundation-led studies.
Clinical laboratories dealing with persistent workforce shortage should consider using the military concept of force multipliers to reduce productivity constraints and maximize limited resources, write Shawn Silver, a pathology resident at Case Western Reserve University, and Jaime Noguez, director of clinical chemistry and toxicology at University Hospitals Cleveland Medical Center. Silver and Noguez describe how the use of robotic force multipliers and automation in their laboratory significantly reduced the amount of hands-on time required by staff.
Scientists at the University of Pittsburgh have developed a device that uses red light to remove carbon monoxide from the blood and oxygenate it in tests involving rats, according to a study in the journal Science Translational Medicine. The device pumps blood from a vein in the leg through a porous membrane where it is exposed to red light.
The World Health Organization said the work to respond to Ebola virus infections in Lwemba, Democratic Republic of Congo, has resumed on a restricted basis after security issues had stalled the efforts. WHO also reported a decline in the number of new cases.
China's medical product regulatory agency has granted IASO Biotherapeutics and Innovent Biologics clearance to launch their Phase Ib/II trial in China to assess the chimeric antigen receptor T-cell therapy candidate CT103A as a treatment for patients with relapsed or refractory multiple myeloma. The agency also granted the therapy Investigational New Drug status.
Singapore's National Environment Agency is expanding a study called Project Wolbachia that uses drones to release sterile male Aedes aegypti mosquitoes carrying Wolbachia bacteria. The project has achieved 90% suppression of urban Aedes aegypti at test sites.
Validation data of an assay for early cancer detection, developed by diagnostic firm Grail, showed the test was able to determine tumor location and more than 20 cancer types with a high degree of specificity. The results are scheduled to be presented at the American Society of Clinical Oncology Breakthrough conference in Bangkok.
A study in the journal Molecular Cancer Research found that bone marrow macrophages could be predictive biomarkers for resistance to the multiple myeloma treatment bortezomib. In tests of human cell lines in animal models, the drug induced formation of pro-inflammatory macrophages that can promote tumor growth, according to researchers.
Johnson & Johnson has pledged more than $500 million over four years to support research and development initiatives with the goal of eliminating HIV and tuberculosis by 2030. J&J is also preparing to launch a second trial of its investigational vaccine for the prevention of HIV in 3,800 men in Europe, North America and South America.
This case study describes how collaboration, appointing champions and using computerized provider order entry systems led to an improved laboratory stewardship program. The study discusses the importance of including relevant stakeholders when considering laboratory stewardship interventions, including physicians, pathologists and lab send-outs staff; achieving complete consensus among these stakeholders; and ordering only those tests that affect clinical management.
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