Dr. Joshua Bauml said liquid biopsies have the potential to be an alternative to tissue biopsies in assessing resistance to cancer treatments. "We draw blood and request urine samples from our patients all the time, and the ability to test this serially is very appealing when we consider the fact that resistance develops over time," Bauml said at the 36th Annual Chemotherapy Foundation Symposium.
Universal screening for hepatitis C virus infection is more cost-effective and efficient than risk-based screening in pregnant women, data show.
Laboratories adopting immunoassays for lipoprotein(a), which are designed to identify individuals at increased risk of cardiovascular disease, should determine providers' expectations on the targeted patient population and on guidelines for Lp(a) levels. Labs and clinicians should be aware of racial/ethnic differences in Lp(a) levels, particularly in African-Americans.
A Series A financing round has pulled in about $3.7 million for Canada-based medical technology firm Rna Diagnostics. Part of the proceeds will be used to commercialize the company's RNA disruption assay.
Chembio Diagnostic Systems' DPP Ebola Antigen System is the second rapid antigen fingerstick test granted emergency use authorization by the FDA to detect the Ebola virus in patients. It is the first that uses a mobile battery-operated reader, which allows it to provide diagnostic results outside of laboratories.
Almost 500,000 uninsured people in five states are expected to gain access to Medicaid coverage following the midterm elections, advocates say. Three states voted to expand Medicaid eligibility, while two others elected governors who have promised to support state legislation expanding their programs.
Cases of Ebola virus infection in the Democratic Republic of Congo have reached 319, with 198 people dead, making it the largest outbreak in the country's history. "The risk of the outbreak spreading to other provinces in the Democratic Republic of the Congo, as well as to neighboring countries, remains very high," the World Health Organization said.
An international panel of medical and academic experts identified a range of priority issues related to toxicity assessment in clinical trials of treatments for hematologic conditions and defined potential solutions. The commission included toxicities unique to hematopoietic stem cell transplantation among the issues, and the recommendations were reported in The Lancet Haematology.
Sangamo Therapeutics will not be submitting an abstract for presentation at the American Society of Hematology's meeting next month for SB-525, a gene therapy candidate for hemophilia A. An additional dose escalation will be carried out in a Phase I/II study before the data are released.
Maternal use of hormonal contraception during or just before pregnancy was associated with a slightly elevated risk of non-lymphoid leukemia in children, according to a Danish population-based study in The Lancet Oncology. The overall risk remained low, researchers said.
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