Taking simple steps to reduce energy, water and hazardous chemical use and being mindful of the environmental effects of daily laboratory activities can turn a clinical laboratory into a more sustainable space, writes Allison Paradise, CEO of My Green Lab. Turning off equipment when not in use, equipping faucets with low-flow aerators, using glassware instead of disposable plastic items and eliminating use of mercury are some changes clinical labs can adopt to reduce environmental impact.
Israel-based startup Diagnoz.me has developed a disposable smartphone add-on device and image analysis software that can be paired to analyze bodily fluid samples at home. The company's "image-analysis software can detect bacteria as accurately as a high-end lab microscope that costs over $100,000," co-founder Ariel Livne says.
In a small trial, researchers found that 16 out of 17 patients with sickle cell disease or beta-thalassemia major who underwent haploidentical bone marrow transplants achieved full donor chimerism or mixed donor-host chimerism after receiving twice the regular dose of total-body irradiation. Only one patient experienced primary graft failure. The findings in the journal The Lancet Haematology suggest that this curative approach should no longer be restricted to patients with HLA-matched donors, researchers said.
Democratic Republic of Congo health officials said 24 new cases of Ebola were reported in multiple locations, bringing the total to 960. Meanwhile, a survey found that Merck's VSV-EBOV vaccine was associated with a lower rate of side effects than reported by healthy volunteers in an earlier study.
An analysis of data involving hemophilia A patients without inhibitors confirmed that regular factor VIII prophylaxis can control or prevent bleeding in adult and adolescent males. Data were published in the journal Haemophilia.
The World Health Organization said sustaining efforts to contain the Ebola virus in the Democratic Republic of Congo will take additional donations of $148 million over the next six months. The CDC announced plans to send experts to provide training.
Pops! Diabetes Care has launched its Pops! one System for use as a virtual care approach to managing diabetes. The system is a glucose meter that attaches to a phone case, transmitting readings to the Pops! app after users prick their finger with a point at the top of the case, and it provides personalized behavior advice.
Diagnostics firm Natera and China-based BGI Genomics have signed a 10-year deal to market the former's custom tumor DNA test in China and develop reproductive health tests in certain markets. Under terms of the deal, BGI will pay Natera $50 million in upfront licensing fees, royalties and future milestone fees, while BGI will receive $6 million from Natera for sequencing services.
The FDA has approved the PD-L1 Assay, developed by Roche unit Ventana, as the first companion diagnostic to identify patients for Genentech's Tecentriq and Celgene's Abraxane combination therapy for triple-negative breast cancer. The test is available on Roche's fully automated BenchMark ULTRA instrument.
A comprehensive analysis has associated a gene-expression signature in blood samples taken from 455 kidney-transplant recipients with T cell-mediated rejection, according to a report in the journal EBioMedicine. "This test could be used to aid in patient management post-transplantation," such as helping to "guide anti-rejection therapy and management; it may help in avoiding unnecessary biopsies, and it may help to confirm BK-virus nephropathy," said researcher Maria Hernandez-Fuentes.
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