Researchers from Japan are developing a blood test to detect a decrease in flotillin protein, an exosome marker that is a key indicator of Alzheimer's disease. "Flotillin detected in less than a drop of blood enables a diagnosis of Alzheimer's disease and mild cognitive impairment at a stage prior to the disease," said researcher Makoto Michikawa.
Researchers developed a pacifier that monitors the glucose levels of babies with type 1 diabetes through the infant's saliva, according to a study published in Analytical Chemistry. The device had good correlation with blood glucose levels when tested in adults, the researchers said.
Researchers from the Rensselaer Polytechnic Institute have found a way to use 3D bioprinting to create living skin with a functional vascular system, and they think their approach has potential for creating grafts that function like human skin. The protocol is described in the journal Tissue Engineering Part A.
A six-month quality initiative implemented at the University of Kentucky Chandler Medical Center resulted in a 16.7% reduction in daily in-patient laboratory test orders for basic metabolic panels, comprehensive metabolic panels, complete blood counts, CBCs with differential and renal function panels. The multidisciplinary initiative also saved approximately 41 liters in total blood volume from expected blood draws and reduced costs by $1.69 million, without an adverse effect on patients, researchers reported.
A study in the Blood Cancer Journal found survivors of chronic lymphocytic leukemia were at greater risk for a second primary malignancy, with the highest risk coming two to five months after CLL diagnosis. The study was based on data from 1973 to 2015 from the Surveillance, Epidemiology, and End Results database.
The FDA has granted 510(k) clearance from the FDA for Becton, Dickinson and Check-Points Health's antibiotic-resistant bacteria molecular screening test using the BD MAX system. The assay detects the five most common carbapenemase genes in about 2.5 hours.
New draft guidance was released by the FDA outlining its recommendation on the development of drugs for chronic hepatitis D, which lacks approved treatments. The 17-page draft provides information to sponsors regarding stages of development, stating that breakthrough therapy, fast-track and priority-review designations are available.
Patients who restarted anticoagulant or antiplatelet drugs following gastrointestinal bleeding had lower rates of mortality but higher rates of renewed bleeding than patients who did not restart the drugs, according to a study in the journal Alimentary Pharmacology and Therapeutics. The study included 871 patients and found that rebleeding rates were higher with anticoagulants than antiplatelet agents.
The reinfection and death of a woman in the Democratic Republic of Congo has raised concerns that people who survive the infection may not all remain immune from contracting the virus again. The World Health Organization and national health officials are drafting new care guidelines for the prevention of reinfection among people who may have incomplete immunity.
Exact Sciences reported revenue of $218.8 million during the third quarter, an increase of 85% over the same period in the prior year, and a net loss of $40.5 million. Test volume numbers for the Cologuard at-home colon cancer test also increased 89% in the third quarter, compared with the same period last year.