Investigators found no significant difference in overall mortality rates at 90 days among 488 patients with severe acute kidney injury and septic shock who were assigned to either early strategy renal replacement therapy, involving treatment within 12 hours of failure-stage AKI diagnosis, or a delayed strategy, involving treatment after 48 hours if there was no renal recovery. The research was published in The New England Journal of Medicine.
The World Health Organization on Wednesday will convene an emergency meeting to discuss whether the most recent Ebola outbreak in the Democratic Republic of Congo should be designated a public health emergency of international concern. DRC officials report that 33 new infections have been confirmed over the last week, and 24 of those cases were fatal.
Dialysis patients in Florida who were affected by Hurricane Michael can seek emergency assistance from the American Kidney Fund, which is giving grants to patients who need to replace lost medications, purchase renal diet foods, pay for transportation to treatment or temporary housing, and obtain other essential items damaged or lost due to the storm.
A clinical chemistry score that combined high-sensitivity cardiac troponin and glucose results with estimated glomerular filtration rate performed better in terms of sensitivity and specificity than high-sensitivity cardiac troponin results alone in stratifying risk among emergency room patients suspected of having acute coronary syndrome, a study found. Adopting the laboratory score could lead to better lab reporting and analytics needed for patient examination, researchers said.
The rate of US children ages 19 months to 35 months who didn't receive any recommended vaccinations rose from 0.3% in 2001 and 0.9% in 2011 to 1.3% in 2017, CDC researchers reported in the agency's Morbidity and Mortality Weekly Report. Another CDC study showed that the overall vaccination rate among those entering kindergarten held steady at nearly 95%, even though the vaccine-exemption prevalence rose for the third consecutive school year.
People who may have been exposed to the Ebola virus have been difficult for health workers to contact in the conflict-torn city of Beni in the Democratic Republic of Congo. "We anticipate that now we'll be looking at least another 3-4 months in order to really stem this outbreak, with a strong focus in Beni and surrounding areas," said World Health Organization emergency response chief Dr. Peter Salama.
Tandem autologous/allogeneic hematopoietic cell transplantation was associated with long-term remission of multiple myeloma for certain patients, according to a study in the journal Haematologica. The study, based on data for 244 patients, found a 10-year overall survival rate of 41% and a 10-year progression-free survival rate of 19%.
India has reported 32 confirmed cases of Zika virus infection in Jaipur. Control and containment operations are underway, and samples are being collected for testing from residents in a 3-kilometer radius of the location of the first reported case.
The recent initial public offering of Allogene Therapeutics raised roughly $300 million. The funds will be used to advance off-the-shelf chimeric antigen receptor T-cell therapies using allogeneic T-cells.
A synthetic DNA vaccine has shown promise in treating the Ebola virus, demonstrating immediate and long-term results in preclinical testing. The research was published in The Journal of Infectious Diseases.