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Patients with type 2 diabetes who had a positive screening for a major depressive disorder were at 2.72-fold increased odds of having low medication adherence, according to a study in the Journal of Diabetes and its Complications. Researchers surveyed 376 patients with a mean age of 56.6 and found that low medication adherence was associated with an A1C level of 8.5% or more, having two of four somatic symptoms and all four cognitive affective symptoms, and a score of more than 10 on the depressive symptoms questionnaire.

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