Vertex, Bristol to conduct midstage trials of hep C combo therapy

04/8/2013 | Genetic Engineering & Biotechnology News

Vertex Pharmaceuticals and Bristol-Myers Squibb signed a non-exclusive deal to initiate two midstage trials of a once-a-day combination therapy for hepatitis C. The trials will test the safety, tolerability, pharmacokinetics and viral cure rates of Vertex's VX-135, a nucleotide analogue hepatitis C virus polymerase inhibitor, in combination with Bristol's daclatasvir, an experimental NS5A replication complex inhibitor.

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