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Non-hormonal options for menopause symptom relief

Non-hormonal options for menopause symptoms

3 min read


Non-hormonal options for menopause symptom relief

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This post is sponsored by EQUELLE®.

Menopause and its related symptoms affect approximately 2 million women a year.1 A recent survey shows 84% of US menopausal women experience disruptive menopause-related symptoms, but 42% have never addressed menopause with a health care provider, emphasizing how little the issue is discussed publicly.2 There is a glaring lack of awareness and knowledge surrounding the topic and its impact on women, and many women are uncomfortable talking about it, even in a health care setting.

At the same time, most health care providers surveyed feel uncomfortable when discussing menopause with patients (80% say they are “barely comfortable”), and only 20% of OB-GYNs receive training on menopause during residency.2

A 2014 review of insurance claims by Yale University review found 60% of American women with significant menopausal symptoms seek medical help, but three-fourths of those women are left untreated, suggesting either a lack of training or lack of options for American OB-GYNs.3

Although one known option is hormonal therapy, there are also a wide range of lifestyle modifications as well as non-hormonal options that can ease the menopausal transition. Changes in diet and exercise routine, along with optimizing sleep regimen, can help alleviate symptoms.

Weight gain is common during menopause and can contribute to a number of issues, including mood and sleep disruption, as well as increasing risk factors for a number of chronic diseases. Finding ways to integrate a healthful, whole-foods diet can help improve overall wellness. Physical activity is important for stress and mood management. Non-hormonal therapeutic options for addressing menopausal symptoms include acupuncture, meditation and supplements.

One such option is EQUELLE®, a science-based, hormone-free supplement clinically shown to help reduce the frequency of hot flashes, supporting women during their menopausal transition. The active ingredient is S-equol, a naturally derived compound of the soy isoflavone daidzein that is produced through the fermentation of soy germ. It is structurally similar to estrogen, and mimics some, but not all, estrogenic activities. Over 10 years of research has shown that EQUELLE helps relieve some of the most disruptive symptoms during menopause in as little as four weeks with optimal results between eight and 12 weeks.

Effects have been shown to include:

  • Reduced frequency of hot flashes*
  • Mood support*
  • Support for general well-being during menopause*
  • Relief from muscle discomfort associated with menopause.*

Patients experiencing symptoms as they go through the menopause transition are looking for a non-hormonal solution, but they may not feel comfortable discussing the topic and requesting treatment. If you have a patient experiencing symptoms like hot flashes, EQUELLE may be able to help. For more on EQUELLE and its active ingredient, S-equol, visit For more on S-equol research, visit


1. The North American Menopause Society. Overview of menopause. Available at: Accessed March 27, 2019.

2. Wolff, J. (2018). Doctors don’t know how to treat menopause symptoms. Available at: Accessed Sept 5, 2019.

3. Sarrel et al. Incremental direct and indirect costs of untreated vasomotor symptoms. Menopause. 2015; 22(3):260-266.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.