Older adults who lived in areas in the top fifth of exposure to nitrogen dioxide and particulate matter smaller than 2.5 micrometers in diameter had 40% increased odds of developing dementia, compared with those who lived in areas with the lowest air pollution exposure, UK researchers reported in BMJ Open. The findings were based on data from 2005 to 2013 involving 130,978 UK individuals ages 50 to 79.
A study in JAMA Network Open found that Medicare fee-for-service spending was $992 lower for each program beneficiary in counties with the highest well-being compared with those with the lowest well-being. The results suggest investing in programs designed to improve population health and social determinants of health will lower health care spending in addition to improving well-being.
The Senate has passed bipartisan legislation that would prohibit pharmacy contract clauses that restrict pharmacist-patient conversations about drug prices, sending the bill to the House for consideration. The Patient Right to Know Drug Prices Act applies to health plans offered in Affordable Care Act marketplaces and by private employers.
A Swedish study in the Journal of the American Medical Association showed that the PET tracer F-18 flortaucipir yielded 89.9% sensitivity and 90.6% specificity in differentiating individuals with Alzheimer's dementia from those with other neurodegenerative disorders. Researchers also found that all five F-18 flortaucipir regions of interest had higher areas under the receiver operating characteristic curves than the three volumetric MRI measures.
Researchers examined 20 patients with stable coronary artery disease and found that delaying NaF-PET scans by three hours after tracer injection prompted a 92% increase in corrected maximum standardized uptake values and 80% higher target-to-background ratios in coronary plaques on average, resulting in the identification of seven additional coronary lesions, compared with the standard one-hour delay. The findings were published in the Journal of Nuclear Medicine.
The World Molecular Imaging Congress named MILabs' VECTor6 imaging system with Broadband Photon Tomography technique, which boosts F-18 PET resolution to 0.55 mm and removes positron range effects for rubidium-82 and iodine-124, the recipient of its Commercial Innovation of the Year award. The system also enables simultaneous imaging of multiple PET isotopes and acquisition of temporal and spatial PET/radiotherapy and PET/SPECT images.
A marketing application was filed with the FDA by Johnson & Johnson unit Janssen Pharmaceuticals for breakthrough therapy-tagged erdafitinib, which is indicated to treat patients with metastatic or locally advanced urothelial cancer and fibroblast growth factor receptor genetic alterations who experienced tumor progression after completing chemotherapy. The submission was backed by data from the midstage BLC2001 trial.
Researchers found that 35.4% of radiology residents reported symptoms of burnout during the second year of their residency, the third-lowest rate among residents in 20 medical specialties. The findings in the Journal of the American Medical Association also showed that career choice regret was reported by 16.7% of radiology residents, which tied for sixth-highest among specialties, but just 6.1% regretted their choice of specialty.
People who walk alone walk at a different pace than when they walk with others, and where they live may affect walking pace, according to a study in PeerJ -- the Journal of Life and Environmental Sciences. Researchers found the walking pace among people in Uganda averaged about 11% faster than the pace of people in Seattle when walking alone.
Employee benefits and vacation time outpaced wage growth this past year, including a nearly 12% growth in employee bonuses and other supplemental pay, according to a report from the Labor Department. Data showed a 4% increase in paid leave, including vacation time.