Researchers from Columbia University Medical Center found that using a native space automated amyloid-beta quantification technique in F-18 florbetaben PET scans of older adults yielded consistently and significantly increased higher standardized uptake value ratios in nearly all brain regions and each histopathological staining level, compared with the standard space approach. The technique, described in the Journal of Nuclear Medicine, also more significantly predicted histopathological staining scores, indicating improved amyloid-beta quantification precision than the standard approach.
Celgene will return the global rights of BeiGene’s anti-PD-1 antibody candidate tislelizumab as a result of its deal with Bristol-Myers Squibb, which will also trigger a $150 million payment. Tislelizumab is under development and is in the last stage of testing as a monotherapy and as a combination for other therapies for hematologic and solid tumor cancers.
The CMS released a proposed rule that would update the electronic prescribing standards and prior authorization process for Medicare Part D. The proposed changes "would reduce the time it takes for a patient to receive needed medications and ease the prescriber burden by giving clinicians the flexibility and choice to complete prior authorization transactions electronically," CMS Administrator Seema Verma said.
The Senate Health, Education, Labor and Pension Committee will begin discussing the Lower Health Care Costs Act backed by Sens. Lamar Alexander, R-Tenn., and Patty Murray, D-Wash., in hearings today. The package includes measures meant to address the cost of prescription medications.
Vertical health care provider integration often impedes competition and results in higher prices, AHIP said in a testimony submitted to a Senate panel as part of a hearing on the issue. To counter the anti-competitive effects of consolidation, AHIP offered several recommendations, including requiring government agencies to examine and address the ways in which they might be promoting consolidation.
The CDC said the number of confirmed measles cases in the US increased by 22 to 1,044 as of June 13, the highest number since 2,126 infections were documented in 1992. The outbreak has spread to 28 states, but most of the new cases occurred in New York.
Health insurance providers are working to address social determinants of health, and hospices are looking to leverage this trend to help patients continue receiving care at home. Building community partnerships to accommodate nonmedical needs may help hospices improve quality of care and patient satisfaction, as well as open new revenue streams.
Researchers created a CRISPR-based system that uses transposons or "jumping genes" to improve gene editing by inserting new DNA sequences without making cuts. Current CRISPR tools for cutting and pasting DNA can lead to adverse side effects.
Breast milk contains immunoglobulin A antibodies that may help protect premature infants from necrotizing enterocolitis, according to a study in the journal Nature Medicine. The study found infants who were breastfed had more IgA-bound gut bacteria than those given formula and that infants who developed NEC were more likely to have been on formula.
The NICU at Gwinnett Medical Center in Georgia is installing 44 closed circuit cameras so parents can watch over their infants when they are not at the hospital. Interim clinical manager Keri Boatwright says the goal is to facilitate a connection between parents and infants.