A study in the American Journal of Psychiatry found that children at high risk for abuse or neglect whose parents received an early parenting intervention on neuroprocessing of parental cues and psychosocial functioning exhibited greater maternal cue-related activation in clusters of brain regions -- including the hippocampus, the cingulate gyrus and the precuneus -- which are commonly associated with social cognition, compared with those in the control group. The findings, based on data involving 68 youths, also showed an association between greater activity in these regions and fewer total behavioral problems.
Researchers studied 47,305 youths who had been referred for alleged neglect or abuse and found that those who scored in the highest 5% risk group by a predictive risk model were more likely to have a medical encounter for treatment of an injury in the follow-up period, compared with those who were in the bottom 50% of risk. The findings in JAMA Pediatrics also showed that the rate of experiencing an any-cause injury encounter was 14.5 per 1,000 in youths referred for maltreatment and identified as highest risk, compared with 4.9 per 1,000 in those at lowest risk.
Patients with chronic kidney disease, type 2 diabetes and obesity had a better chance of achieving CKD remission after gastric bypass surgery, compared with patients who received best medical treatment, according to a study published in JAMA Surgery. Researchers reported an 82% CKD remission rate for Roux-en-Y gastric bypass surgery patients after 24 months, compared with 48% for those who just received medical care.
An increase in the small molecule cholic acid-7-sulfate after bariatric surgery may be the reason diabetes improves in patients after surgery, according to research conducted at Harvard Medical School. The discovery could lead to drug therapies to treat obesity, researchers said.
A rapid diet assessment and counseling tool may help clinicians talk with patients about healthful eating habits during a physician visit, according to an American Heart Association scientific statement published in Circulation: Cardiovascular Quality and Outcomes. Researchers evaluated 15 tools and found the top three were the 14-item Mediterranean Diet Adherence Screener, the 16-item Rapid Eating Assessment for Participants and the eight-item version of the Starting the Conversation tool.
Interviews conducted from March to May among nationally representative samples in Australia, Canada, France, Germany, the Netherlands, New Zealand, Norway, Sweden, the UK and the US found that Americans reported greater mental and financial stress during the COVID-19 pandemic. "It's no secret that at a time when countries around the world are reopening, ours is still struggling to return to work and daily life," Commonwealth Fund President David Blumenthal said.
Moderna announced last week that it will now include people living with HIV that have "controlled HIV who are not otherwise immunosuppressed" as participants in their Phase III trial to evaluate their COVID-19 vaccine candidate, after being pressured by concerned groups when it originally said that it would exclude PLWH from the trial. The FDA has urged drugmakers to include those with other health conditions, older individuals, and racial and ethnic minorities in their vaccine research.
Emergency use authorizations were granted by the FDA for three ventilator-related devices as well as a new umbrella provision for surgical masks that meet certain criteria as personal protective equipment in health care settings during the pandemic. The three ventilator-related EUAs were given to the Subsalve Oxygen Treatment Hood, the Vortran GO2Vent with positive end-expiratory pressure valve and the nHale device.
The 8th U.S. Circuit Court of Appeals agreed with the Pharmaceutical Care Management Association in ruling that a North Dakota law restricting pharmacy benefit managers affects insurance plans subject to the Employee Retirement Income Security Act and is therefore preempted by ERISA.
Registered dietitian Katey Davidson says research does not support the use of herbal detox products to remove toxins from the body or for weight loss, blood sugar control or other health claims. The body already has a detox system using the liver, skin, intestines and kidneys, Davidson says, and claims that people feel better after a detox may be linked to healthful behaviors such as eating a diet of nutrient-dense whole foods.